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aip_crisis

Yes and yes.


keeper4518

Yup. When I eat foods with too much histamine I feel similar. It causes me to feel on the edge of a panic attack (that's how I describe it anyways). I am also more likely to feel overwhelmed by little things and more stressed out. So yes, it can affect all sorts of things


jmorgannz

Histamine is a stimulating neurotransmitter. So yes. It's a different effect to histamine in the wider body; but could indicate you have a brain histamine metabolism issue - perhaps SLOW HNMT enzyme. Could also indicate you are undermethylated and in need of methyl donors.


Z3R0gravitas

Don't get it myself. But I believe it's said to come from the body compensating for histamine's vasodilatory effect (lowering blood pressure), by releasing adrenaline (which has an opposite vasoconstrictive effect) and/or via autonomic nervous system action.


Jollyfroggy

This explains much... do you happen to have any sources for further reading?


Z3R0gravitas

So, when I was looking at these things, \~8 years back ([my blog post](https://lewyland.blogspot.com/2013/09/health-revolution-part-1-diving-into.html)), I was reading Genny Masterman's book and The Low Histamine Chef web content. E.g an [interview article](https://healinghistamine.com/blog/interview-dr-georgia-ede-on-histamine-anxiety-and-depression/) of her's which mentions adrenaline (but I'm sure you can Google up more). Good luck.


Jollyfroggy

Thankyou for supplying these articles. I have read the first and I will digest the rest shortly. I had a similar experience in struggling to find an NHS doctor to help me... my current dietician is amazing, but a previous gp... effectively took the piss out of me as I was basically crying... sad times. Im sorry the dao pills doesn't work for you. Similarly i tried a diasin pill treatment around 3-4 years ago, which did nothing. But when I tried something recently (daosin) it was game changing... One thing I have noticed is that a lot of low histamine books contain things like egg, which can be histamine high.. depending on how they are stored, so a food diary has been useful. An odd effect of my condition 8s that I will sometimes spend 1-2 hours in the morning with a pulse of around 30 bpm, ot found a good explanation of that yet... Anyway, thanks for sharing!


Z3R0gravitas

I'm currently reintroducing some egg, after about 7 years without; Yorktest (IgG) foos intolerance screening showed I don't have antibodies to it anymore. But yeah, it's tricky with any protein source. Plus I remember reading it may form structures that damage the gut... But I need to add more stuff back; still out diary, yeast and wheel, too. And I developed osteoporosis over the rime since exclusions. Though for no obvious medical reason yet found. (I'm thinking collagen formation issue, as common 8n ME/CFS.)


-mjneat

That blog post… a lot of it sounds like me. I’ve been diagnosed adhd, recently been pondering if I’m ASD as well. I dove into the gut brain connection and diet related to Asperger’s and came across this line of enquiry. It seems likely to me that a lot of my family (all immediate except dad) possibly suffer from this. Me and my brother have had MH issues, so did my grandmother, mother suffers with migraines, tinnitus, a bit of depression and a lot of inflammation. My other brother copes well I’m not even sure it’s an issue(if he’s the same) but he’s had chronic gut issues that have required surgery. Interestingly he’s a rugby player and in good shape but his diet is heavy on steak. He seems to have none of the MH issues but a lot of the physical with his gut(he may not be telling me of any MH issues though). I find it interesting people say a carnivore diet can help Asperger’s symptoms but steak is high in histamine afaik so maybe he’s treating the MH aspect with the fats in the meat but the increase histamine is causing what he experiences. I googled the link between Asperger’s and histamine, nearly 100% have a histamine intolerance…


Z3R0gravitas

>the link between Asperger’s and histamine, nearly 100% have a histamine intolerance... It's been weird, recently, seeing my ADHD (& ASD) world collide with ME/CFS, online, via histamine intolerance. (Even though I noted, at the time of low histamine diet, qualitive improvement to some of my attributes I'd considered ASD spectrum.) Specifically, I've been replying with my food intolerance experiences to @ roryreckons (Twitter) popular tweets about going low histamine himself and seeing improvements in his ASD/ADHD/etc (he's worth a follow for you I think). E.g.: [https://twitter.com/Z3R0Gravitas/status/1478589195258052608](https://twitter.com/Z3R0Gravitas/status/1478589195258052608) ​ >but steak is high in histamine It might depend a bit. If it's hung to deliberate age and tender, then yeah, it won't be great. I avoid beef steak but eat a lot of fresh lamb. And chicken and salmon, because I can tolerate so few other protein sources, in terms of IgG antibody reactions too (confirmed by multiple YorkTest ELISA panels). There might be accidental benefits of a 'carnivore' diet, like excluding wheat, or FODMAPS, or processed foods, etc..? Also, in the extreme, it may be so low carb as to enter ketosis. This can work well for some/many with ME/CFS, \*if\* you can enter this state. Anti-inflammatory and might circumvent mitochondrial energy metabolism blocks. Ketosis requires good thyroid function and just doesn't work for some, from what I've seen. I've not had enough food options to feel I can try it myself, with histamine and other intolerances. And I'm already unhappy with the large amount of meat I'm now eating.


-mjneat

Did you write a part 2?


Z3R0gravitas

>Did you write a part 2? Sadly, no. It was going to be about the methylation cycle and related supplements. I was hyped about that, as it was turbo-charging my energy for a month or so. But both the dietary and supplement energy/cognitive improvements slowly fell off over time, so I wasn't as able (or as excited) to blog about it. Also did a screen detox for a couple months, to try treating my delayed (non-24-hour) circadian rhythm. I recently described a bunch of it in this thread to Rory on Twitter, too (nutri-genomics is complex to get into, with a lot of uncertainties, contradictions, expense, effort): https://twitter.com/Z3R0Gravitas/status/1481647394437566467


J894ty

Yes, allergies can trigger the fight or flight response. They can also cause anxiety.


Jollyfroggy

Histamine absolute screws with my social anxiety.... You can get soem stuff to deal with this in the short term, talk to your doctor. Also have a think about meal time dao


Full_Big_4847

Yes it can! Have you tried histamine-free probiotics? Try histamine-free probiotics that include bifidobacterium longum and lactobacillus plantarum, or at least one out of the two. Both of these probiotic bacteria, which are completely natural, degrade histamine. You have them in your gut now but like most of the population, you probably don't have enough. They can make a huge difference.


kml6389

Is there a specific brand of probiotics you’d recommend?


Full_Big_4847

Smidge sensitive works wonders with me..a little pricey but cheaper than psychiatrists


Full_Big_4847

Takes about 3 weeks to a month to kick in, begin with a small dose and slowly step it up


Full_Big_4847

Please tell me how it goes I'm curious


kml6389

Do you buy it directly from the company?


Full_Big_4847

Yes. The company is called smidge. Weird


Friedrich_Ux

Yes, histamine is a vasodilator which causes tachycardia. Its also a neurotransmitter responsible for vigilance (anxiety) and arousal.


lovetimespace

For me it seems to. I used to have this feeling in my heart area constantly that is similar to what one feels before crying, like a tightness, though for me it wasn't connected to an emotion of any kind. I recently switched to eating low histamine, and I just realized yesterday that it has been about a month since I last noticed it and it used to be a constant thing. When I've described it to doctors before they've made me feel like I'm imagining it.


ApronNoPants

This. I get this, too. It feels tense, like this tightness in my chest. My heart might flutter or beat faster. It sort of feels like a tiny panic attack without the anxiety. Benadryl makes it stop, so I think it's histamine.


BellyUpHufflepuff

YES


PeanutImpossible115

Yea. That is mainly what makes it hard for me to sleep if I have eaten something "bad" to late in the eventing. Heart palpitation, mental hyperactivity, and stomach distension.